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Dalacin T Topical Solution: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Dalacin T Topical Solution - General Information

An antibacterial agent that is a semisynthetic analog of lincomycin. [PubChem]

 

Pharmacology of Dalacin T Topical Solution

Dalacin T Topical Solution is an antibiotic, similar to and a derivative of lincomycin. Dalacin T Topical Solution can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.

 

Dalacin T Topical Solution for patients

This medicine is used to treat various bacterial infections, such as pneumonia
or other respiratory conditions such as COPD. It can also by used in patients
with cystic fibrosis or patients who have received an infection while being
hospitalized, or who have bacteria in the blood (bacteremia). In children,
this medicine is commonly used to treat ear infections (otitis media), pneumonia,
sore throat (pharyngitis) or tonsillitis. Take the medicine orally as directed.
This medicine can be taken with or without food. And remember to finish all medication
unless your doctor has advised you otherwise. It is also important to avoid taking
aluminum or magnesium-containing antacids together with this medicine. If you take
antacids, separate them from your antibiotic by at least 2 hours.

 

Dalacin T Topical Solution Interactions

Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between clindamycin and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.

 

Dalacin T Topical Solution Contraindications

Clindamycin hydrochloride is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.

 

Additional information about Dalacin T Topical Solution

Dalacin T Topical Solution Indication: For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci) Mechanism Of Action: Systemic/Vaginal-Dalacin T Topical Solution inhibits protein synthesis of bacteria by binding to the 50 S ribosomal subunits of the bacteria. Topical-Dalacin T Topical Solution reduces free fatty acid concentrations on the skin and to suppress the growth of Propionibacterium acnes (Corynebacterium acnes), an anaerobe found in sebaceous glands and follicles. Drug Interactions: Aluminium The aluminium salt decreases the absorption of lincosamidesAtracurium The agent increases the effect of muscle relaxantDihydroxyaluminium The aluminium salt decreases the absorption of lincosamidesCyclosporine Decreases the effect of cyclosporineDoxacurium The agent increases the effect of muscle relaxantGallamine Triethiodide The agent increases the effect of muscle relaxantMetocurine The agent increases the effect of muscle relaxantMivacurium The agent increases the effect of muscle relaxantPancuronium The agent increases the effect of muscle relaxantPipecuronium The agent increases the effect of muscle relaxantRocuronium The agent increases the effect of muscle relaxantSuccinylcholine The agent increases the effect of muscle relaxantTubocurarine The agent increases the effect of muscle relaxantVecuronium The agent increases the effect of muscle relaxantAttapulgite The aluminium salt decreases the absorption of lincosamidesKaolin The aluminium salt decreases the absorption of lincosamides Food Interactions: Take with food. Generic Name: Clindamycin Synonyms: Clindamycin Hcl; Clindamicina [Inn-Spanish]; Clindamycin Hydrochloride; Clindamycin Phosphate; Clindamycine [French]; Clindamycine [Inn-French]; Clindamycinum [Inn-Latin] Drug Category: Anti-Bacterial Agents; Lincomycins Drug Type: Small Molecule; Approved; Investigational Other Brand Names containing Clindamycin: Chlolincocin; Cleocin; Cleocin Hcl; Cleocin Pediatric; Cleocin Phosphate; Cleocin T; Cleocin T Gel; Cleocin T Lotion; Cleocin T Topical Solution; Clinda-Derm; Clindagel; Clindesse; Clindets; Clinimycin; Dalacin; Dalacin C; Dalacin C Flavored Granules; Dalacin C Phosphate; Dalacin T Topical Solution; Evoclin; Sobelin; Absorption: Rapidly absorbed after oral administration. Absorption of an oral dose is virtually complete (90%), and the concomitant administration of food does not appreciably modify the serum concentrations; serum levels have been uniform and predictable from person to person and dose to dose. Toxicity (Overdose): Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin. Protein Binding: 92-94% Biotransformation: Hepatic Half Life: 2.4 hours Dosage Forms of Dalacin T Topical Solution: Solution IntravenousPowder, for solution OralLiquid IntravenousCapsule OralCream IntravaginalSolution TopicalCream TopicalLiquid Intramuscular Chemical IUPAC Name: (2S,4R)-N-[2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide Chemical Formula: C18H33ClN2O5S Clindamycin on Wikipedia: https://en.wikipedia.org/wiki/Clindamycin Organisms Affected: Enteric bacteria and other eubacteria